Thursday, August 8, 2019
Interpersonal communication about When Harry met Sally movie Essay
Interpersonal communication about When Harry met Sally movie - Essay Example One of the producers and writer, Nora Ephron won an Oscar award. The main characters, Harry and Sally whose real names are Billy Crystal and Meg Ryan were also nominated as the best actor and actress. The film received critical reviews, which were positive (Internet Movie Database, 1990). Some of the most credible critics cited that the film had some of the most entertaining scenes and funny. The theory proposes that relational closeness always progresses from a superficial state to one which is intimate (Kanu, 2008). Harry and Sally’s relationship only grew when they were alone after separating from their lovers. For example, Sally had broken up with her fiancà © Joe and had to disclose it to Harry. In another scene, Harry is seen alone (Reiner, 1989). Similar to what the theory proposes, the closeness between two people develops as a result of self-disclosure. The RDT theory posits that relationships between people always reflect the tensions existing when people are communicating which usually arises from conflicts (Kanu, 2008). In addition, the theory proposes that relationships focus on the opposing behavior of people. In the film, it is clear that Harry and Sally began to regret because of spending a night together. The characters depicted a sense of guilt in different scenes (Reiner, 1989). As proposed by the theory, there are opposing tendencies because a relationship cannot exist without parties sacrificing their self-rule. Harry said he felt it was a mistake. While Sally agreed to Harry’s opinions verbally, her non-verbal tone in one of the scenes indicated she did not feel it was a mistake. The film confirms that the concept of just being friends and not lovers is not true. The theory proposes that when there is an interaction between people, the uncertainty between them reduces (Kanu, 2008). The theory presumes that when the relationship is beginning to grow, there are many doubts. Harry and
Choose any contemporary theme and write a review of that theme by Essay
Choose any contemporary theme and write a review of that theme by using a variety of secondary sources. (Safety and Security in - Essay Example This elevates the issue of safety in airports as of considerable concern in regions that are considered as major destinations for tourists. This paper looks into safety and security in airports in relation to tourism. Introduction The contemporary world has witnessed dramatic changes since the rise of globalization. Based on the heightened incidence and severity of terrorism related incidences, individual’s feelings of safety (whether physical or psychological) have been challenged. The travel and tourism sector have considerably been bruised at various levels, accompanied by growing concerns on safety and security of destinations. The resultant sense of insecurity has yielded to increase screening within airports in a bid to thwart occurrence of any terrorism related incidences. Passengers and air cargo are the two main entities that pose the highest treat to the security and safety of airports. Passengers are considered as a serious threat due to the increased number of terr or activities occurring in airports (Sweet 2009, p.52). Even prior to the 9/11, the society was conscious of the risks associated with being at the wrong location at the wrong time; however, the 9/11 attack brought to the limelight how interconnectedness of the world and the society was awakened to the risks occasioned by the interconnections. The global aviation immediately launched tighter travel rules, restrictions, and regulations in a dramatic attempt to thwart a repetition of the incidence. The changes heralded within the passenger travel experience right from check in to disembarking have been rendered non-negotiable. As a result, the process of travel has been made increasingly complex and time consuming (Sonmez, Apostolopoulos and Tarlow 1999, p.13). The safety and security of airports remains an ongoing challenge and continues to evolve as air traffic rises. The threat presented by crime and terrorism has over the years increased necessitating enhanced security and safety in airports. Indeed, the public has had an enhanced sensitivity towards aviation and airport security owing to the concern that criminality may yield to vulnerabilities that could be exploited by terrorists. The central aim of airport security centres on preventing ‘unlawful interference’ with the could yield to fatalities among the passengers and crew major airports continue to be critical infrastructure for the health of the economy and people’s lives and livelihood, and the possible targets for the severe crimes and terrorism (Sonmez, Apostolopoulos and Tarlow 1999, p.14). Terrorism and crime are unique, but possibly overlap, but at its most fundamental place, an environment characterized by lax security can avail opportunities for terrorists to take advantage of the weaknesses in airport security. However, with the growing surveillance within airports, critics have argued that the heightened security screening at airports is increasingly heralding misery to h oliday travelers. Critics point out that government agencies pursuing to make journeys secure render plane trips unpleasant, which encourages people to take the option of travelling by road (where possible). Discussion Terrorists target airports largely because of the social and economic damage that can arise once an airport has suffered a terror attack. The 9/11 terror attack motivated all leading airports to pay keen attention on improving the
Wednesday, August 7, 2019
The Iliad And The Epic Style Essay Example for Free
The Iliad And The Epic Style Essay ‘Epos’ which is the root Greek word for â€Å"epic† means , â€Å"early, unwritten narrative poetry, celebrating incidents of heroic traditions.(Rees.1966). High seriousness and elevated style are associated with epic, which is evidenced in the convention of Invocation at the start of an epic. In Iliad the poet invokes the muse to assist his dedicated labour: â€Å"Sing Goddess the wrath of Achilles Pleiades/the ruinous anger that woes on the Danna’s brought.†Aristotle in his Poetics describes epic as seeing life as a whole. We see in the Iliad, the epic song as the expression of an entire nation or race, the epic spans a long period of action (at least 10 years of siege and conquest of Troy by the Achaeans). Critics named as ARCHITECTOINICS, the controlled power and design of the epic, in which the poet managed a vast canvass spanning oceans and including the gods in its scope; at the same time never wavering from its central design: the revenge of Achilles and the conquest of Troy are epic subject of the Iliad. Homeric similes and epithets became conventions following the Iliad where Homer constantly engages stock epithets like â€Å"fleet-footed Achilles†,†wine-dark sea†or â€Å"rose fingered dawn†. The epic simile is a device by which the poet would temporarily deviate from his subject while he is making a long drawn out comparison, which in itself stands like a descriptive poem independent of the subject. For example the reaction of Hector on hearing the encouraging words of Apollo in Canto 15 of the Iliad, where the poet launches a detailed comparison of a horse  highly descriptive and grand in its flow, as a parallel to the reviving spirits of Hector.(â€Å"Like a stalled horse fed to the full in the manger/breaks loose from his halter..etc.†) Other conventions like war council, elaborate games and competitions started with Iliad where Achilles is shown throwing a grand Game show after the funeral of his friend Petroclus. The intervention of gods in the destinies and affairs of men is a constant epic feature, called the â€Å"epic Machinery†. The seeds of disaster were in the Olympian incident of Paris son of Priam and prince of Troy acting as Judge in a Beauty competition among Goddesses, Aphrodite, Hera and Athena. Paris decides in favor of Aphrodite as she grants his wish of getting for wife the most beautiful woman. He meets Helen ,wife of Menelaus king of Greece, and abducts her to Troy and thus the Great War starts. It is God Apollo who guides Paris to kill Achilles by sending an arrow at his heels; the fire gods fashion the armor for the invincible Achilles.The gods represent inexorable Fate,in whose grip men are powerless; in whose hands men are puppets. The personae are all divine in origin too. Helen and Achilles’ parentage goes back to Zeus and the sea nymph Thetis respectively; Zeus Athena and Hera have direct stakes in the war, which is but an extension of their strife to control one another. Catalogues of chieftains who participate in the war and the list of the ships launched by Menelaus, which again are part of epic conventions, give an exalted setting to the heroic struggle. The revenge of Hector, the wrath of Achilles, the prolonged siege of Troy provide the grand and solemn background against which the characters like Agamemnon Ajax and Hector acquire supernatural stature. The Iliad has highly descriptive passages on the life in Troy, the tragic aspects of war, on friendship and simple aspects of life. The scene of Hector taking leave of his wife is immortal poetry, and the epic itself is a moving expression of heroism high Idealism. And patriotism. The Heroes themselves are partly historic and partly mythical, legendary characters.`                                              REFERENCE: S.O. Andrew M.J. Oakley, (translators) Homer’s Iliad, 1960.London JM Dent SonsLtd. RJ Rees, An Introduction To English Literature,(p.46-50).1966.Macmillan,London.                                                  [emailprotected][emailprotected][emailprotected][emailprotected][emailprotected]_
Tuesday, August 6, 2019
A terribly strange Bed Essay Example for Free
A terribly strange Bed Essay Therefore they are encouraged to read further on. The things, such as chill wind, affect the readers touch sense. All of the senses are appealed to, and therefore the readers are able to feel more involved and believe they are included in the mystery. The 1st person narrative is important in this story because although we have been slightly detached from the story we are not directly involved in the actions but are more of a spectator of the events. We automatically begin to piece together the pieces of the mystery rather than getting involved in the story. We only get the viewpoint of Watson describing Holmes and Helens experience. It is not narrated by a protagonist but by a neutral to the story having no reason to lie or exaggerate as he plays such a small part in the plot. A terribly strange bed is the same genre as the speckled band but Wilkie Collins creates suspense differently to Conan Doyle, for one the main protagonist writes the story and describes his own feelings of whats going on, so we may get a slightly more exaggerated storyline to what actually happened but this just adds to the excitement and tension, also there will be no important information missed out. Wilkie Collins creates tension differently by using MFs naivety of the back streets of Paris to play with the audiences mind, they will be shouting at him to not do what hes doing but because he not street wise he thinks he can go to these casinos and not be in an danger whatsoever. Let us go somewhere where we can see a little poverty stricken gambling He doesnt understand the implications of going to such a place. MF is the perfect victim in this story he is young, rich and also drunk at the time he is gambling, it would be easy for someone like the French soldier to get him under false pretence and then rob him of all his winnings. One of the main differences between these two stories is that in Wilkie Collins story we dont suspect a thing until three quarters into the story, we know that he is susceptible to such doings but we have to suspicion because of how nice everyone is being, its not until the nurse makes the mistake of putting to much sleeping drugs into the coffee that keeps MF awake, we realize the full extent of whats happening to him, we relive the crime as its happening whereas in Conan Doyles story. The crime has already happened an Holmes is trying to solve it therefore it is necessary for him to use a person who is not involved in the story to be a Narrator whereas if Wilkie Collins did this then the story would be a complete failure because we would know he survives, yes there would be an adventure but it wouldnt grab the audiences attention and they wouldnt feel involved in the story. Therefore I think both authors go about creating mystery and tension the best possible way because if they swapped round and Holmes was telling the story then the audience wouldnt want to get involved and the same with a terribly Strange bed Both authors create suspense in their own way that in my opinion are as effective as each other but I felt more eager to turn over the page in The Speckled Band. Also the description of the setting is successful in creating the most suspense, as the use of darkness suggests something is going to happen. We dont find out a lot about the setting in A Terribly Strange Bed but it his little relevance to the story. Show preview only The above preview is unformatted text This student written piece of work is one of many that can be found in our GCSE Arthur Conan Doyle section.
Monday, August 5, 2019
Relation between Serum Apelin Level and CAE
Relation between Serum Apelin Level and CAE Decreased Apelin Levels in Isolated Coronary Artery Ectasia M.Zihni Bilik, M.Ata Akal, Halit Acet, Abdulkadir Yaldaz, Murat Yà ¼ksel, Nihat Polat, Mesut Aydan, Mustafa Oylumlu, Sait Alan ,Faruk Ertaâ„ ¢Ã‚ ¹  ¹Department of Cardiology, Medicine Faculty, Dicle University, Diyarbakr, Turkey  Abstract Introduction: Etiopathogenesis of coronary artery ectasia (CAE) is completely unknown. Most of CAE develop with atherosclerosis. Association of atherosclerotic coronary artery disease and apelin has been examined in previous studies. In isolated coronary artery ectasia the role of plasma apelin has not been studied yet. Aim: In this study, we investigated the relation between plasma apelin levels and coronary artery ectasia. Material and methods: Study population included totally 54 patients. 26 patients with isolated CAE (53.6 ±8.1 years ); 28 patients as control group with normal coronary arteries (51.6 ± 8.8 years) and with similar risk factors and demographic properties . Apelin levels were measured using an enzyme immunoassay (ELISA) . Results: Apelin levels in CAE group were significantly lower [apelin= 0.116ng/ml (0.086-0.319) ] than those in control group [0.689ng/ml (0.077-1.067) ] (P =0.033).Glucose, creatinine,total cholesterol, triglyceride, LDL-C, HDL-C levels were not significantly different between groups (P >0.05). Conclusions: In this study we showed that patients with isolated CAE have decreased plasma apelin levels. Therefore there may be an association between decreased plasma apelin level and isolated CAE. Key words: apelin, coronary artery ectasia, atherosclerosis Introduction: Apelin is an adipocytokine and endogenous ligand for the angiotensin-like 1 receptor (APJ). The function of apelin is not clear in the cardiovascular system. Apelin may play an opposite role to the renin-angiotensin-aldosterone system as a compensatory mechanism. It is reduced in patients with heart failure.[1] Increased apelin expression has been found in coronary vessels, cardiomyocytes, large conduit vessels [2] vascular smooth muscle cells, and endothelial cells.[3] Some functions of apelin have been described, such as positive inotropism [4] ,endothelium-dependent vasodilation [5],cardiac contractility,[6] and the reduction of vascular wall inflammation. CAE has been defined as abnormal dilatation of a segment of coronary artery that 1.5 times larger than the diameter of adjacent normal segments of artery.[7] The incidence of CAE has been reported to account for 0.3% to 4.9% in patients underwent coronary angiography. [8] Although the exact mechanisms leading to CAE are not clear up to now, atherothrombosis, endothelial dysfunction and vasculit have been suggested as possible responsible factors. CAE has also been reported in association with various conditions such as congenital coronary anomalies, connective tissue diseases, and vasculitis and failed smooth muscle cells. [9,10] Apelin has a role in endothelium-dependent vasodilation. CAE may dependent to endothelium-dependent vasodilation mechanism. [5] So there may be relation between apelin and CAE. In our knowledge there is not any study in the literature about apelin and CAE. Aim: In this study we aimed to examine the relation between serum apelin level and CAE. Material and methods: Study population included totally 54 patients that were admitted to Cardiology Department of Dicle University. Twenty six patients with isolated CAE ( 53.6 ±8.1 years ) as CAE group and 28 patients as control group with normal coronary arteries that proven angiographically (51.6 ± 8.8 years) with similar risk factors and demographic properties to CAE group were included . Cases who had malignancy, heart failure ,acute coronary syndrome, renal disease, collagen tissue diseases, vasculitis,coronary artery disease were excluded from the study. The study was approved by the Local Ethics Committee and informed consent was obtained from each patient. Study design: All patients underwent detailed physical examination. Body mass index (BMI) was calculated as weight divided by square of height. Clinical laboratory analyses were performed in Dicle University Biochemistry Laboratories (Diyarbakar, Turkey). Biochemical tests were performed by Abbott C16000 (USA) biochemical autoanalyzer with original kits and hematological counts were measured by an automated hematology analyzer (Abbott Cell-Dyn 3700; Abboott Laboratory, Abbott Park, IL) in peripheral venous blood samples . Standart methods were used to measure total and high density lipoprotein cholesterol (HDL),triglycerides and fasting glucose. Serum obtained by centrifuge was stored at −80 °C until analysis for apelin measurement. These were studied at the Biochemistry Laboratory of Dicle University .Apelin levels were measured using an enzyme immunoassay (ELISA) (Phoenix Pharmaceuticals, Inc., California,USA) according to the manufacturer’s instructions, and expressed as ng/ml. Evaluation of coronary artery ectasia by coronary angiography Coronary angiography was routinely performed using the Allura Xper FD10 (Philips, Amsterdam, The Netherlands) through femoral artery by Judkins technique without use of nitroglycerine. The contrast agent was Iopamiro 370 (Bracco, Milan, Italy) that used in all patients. Each angiogram was evaluated concurrently by two interventional cardiologists who were blinded to the study and to each other. Angiographically CAE was accepted when diameter of dilated segment of coronary artery was 1.5 times larger than adjacent normal segments. Statistical analysis Data were analyzed with SPSS software version 18.0 for Windows (SPSS Inc, Chicago, Illinois). The Kolmogorov-Smirnov test was used to verify that continuous variables were normally distributed. Continuous variables are listed as mean  ± standard deviation, categorical variables are listed as percentages. The independent sample t-test or Mann-Whitney U test was used for continuous variables and the chi-square test for categorical variables. Statistical significance was defined as p Results: The study was included a total of 54 patients. CAE group included 26 patients with coronary ectasia (mean age 53.6 ±8.1 years) and %73.1 (n=19) of patients were male. Control group included 28 control patients with normal coronary arteries (mean age 51.6 ± 8.8 years) and 64.3% (n =18) of patients were male. There was no difference between two groups regarding basal demographical data (P>0.05). Demographic characteristics of the groups are presented in Table 1. We found apelin levels in CAE group significantly lower [apelin= 0.116ng/ml (0.086-0.319) ] than those in control group [0.689ng/ml (0.077-1.067) ] (P =0.033). Glucose, creatinine,total cholesterol, triglyceride, LDL-C, HDL-C levels were not significantly different between groups (P >0.05). Table 1: Baseline characteristics of the study population Ectasia Grup (n=26) Control Grup (n=28) P value Age (years) 53.6 ±8.1 51.6 ± 8.8 0.38 Male n(% ) 19 (%73.1) 18(%64.3) 0.49 Hypertension n(%) 15 (%58) 12(%43) 0.18 Diabetes Mellitus n(%) 4 (%15) 6 (%21) 0.57 BMI (kg/m ²) 28.1 ± 4 26.7  ±4.2 0.24 Smoking n(%) 13 (%50) 12 (%46) 0.79 Glucose mg/dl 106 ±20 124 ±53 0.1 Creatinine mg/dl 0.86 ±0.2 0.82 ±0.1 0.38 Total cholesterol mg/dl 196 ±47 195 ±37 0.98 LDL mg/dl 128 ±42 113 ±33 0.14 HDL mg/dl 41 ±10 40 ±10 0.92 Triglyseride mg/dl 145 ±77 184 ±115 0.15 Apelin ng/ml 0.116 (0.086-0.319)* 0.689 (0.077-1.067)* 0.033 *Median and interquartile range used. BMI:Body mass index ; LDL: Low-density lipoprotein cholesterol; HDL: High density lipoprotein cholesterol Figure-1: Comparison of the plasma apelin level between CAE and control group. P=0.033 Discussion : CAE has been defined as abnormal dilatation of a segment of coronary artery that 1.5 times larger than the diameter of adjacent normal segments of artery. [7] The etiology of CAE is not fully understood. Various mechanisms are thought to be the reason of CAE. Approximately a half of CAE is due to atherosclerosis of coronary artery. Atheromatous ulcerations in coronary artery or significant stenosis has been described in patients with ectasia.[11,12] Cardiovascular system is the main target of apelin and its receptor APJ . In regulation of cardiovascular homeostasis, apelin may have an important role.[13] Positive inotropism, vasodilation, decreased blood pressure and diuresis are some effects of apelin on cardiovascular system . Therefore apelin may have an antagonistic effect to the renin-angiotensin-aldosteron system .It is reduced in patients with heart failure.[1] Relation between apelin and coronary artery disease especially atherosclerosis is known. Kadoglou et al. showed that apelin concentrations are lower in CAD patients and it is negatively correlated with severity of CAD. [14]. Additionally, decreased apelin levels are observed in subjects with stable angina. Plasma apelin may have a role in the progression and destabilization of atherosclerotic plaques.[15]. Attenuation of the vessel wall has been shown by Rath et al. in nonatherosclerotic forms of CAE .In their study vessel media degeneration and smooth muscle cell replacement by hyalinized collagen with intact vessel intima has been demonstrated.[16] In the pathogenesis of CAE, loss of the musculoelastic components of the vessel media have an important effect. [12,17] Several factors other than atherosclerosis have a role in development of CAE such as endothelial dysfunction, vasculitis, congenital coronary anomalies, connective tissue diseases [9,10], oxidative stres, vascular smooth muscle proliferation, abnormal collagen synthesis and increased inflammatory response. [18] Li L. et al. showed that apelin have a regulatory effect on proliferation of vascular smooth muscle cell and nitric oxide production.[19] Nitric oxide is a potent vasodilator and plays important roles in protecting the cardiac vascular system against myocardial damage. It inhibits leukocyte adhesion ,platelet aggregation and vascular smooth muscle cell proliferation. [18] In some studies there was a relation between apelin and nitric oxide. It is demonstrated that in the rat model, myocardial damage significantly reduces by oxidative injury reduction and enhancement of nitric oxide production when rats treated with apelin in postinfarct period.[20] Tatemoto K., et al. reported that apelin may be present in the endothelium and reduce blood pressure via nitric oxide dependent mechanism.[21] Additionally polymorphism in the endothelial nitric oxide synthase gene has been explored in several studies in patients with CAE. [22] According to this ,impaired nitric oxide dependent vasodilation mechanism may consist to be the reason of ectasia. Malyszko et al. reported that in patients with transplanted kidneys apelin level is correlated with intracellular adhesion molecule, adiponectin and the presence of coronary arery disease in patients with transplanted kidneys. [23] Apelin is a member of adipocytokin like adiponectin. Dagli N. et al. examined a negative correlation between coronary artery ectasia diameter and plasma adiponectin level .[24] Also in our study we obtained similar results that plasma apelin level in isolated CAE patients is significantly lower than in controls. According to recent data adiponectin and apelin have cardioprotective effects . Despite exact mechanism is not clear it seems that, both of them protect vessel from atherosclerosis and ectasia. However, further studies are required to show the role of apelin in development of CAE. Conclusion : In this study we showed that patients with isolated coronary artery ectasia have decreased plasma apelin level compared with normal coronary arteries. According to these data we suggest that apelin may have a role in developing CAE. Limitations of the study Because isolated CAE is rare entity ,the number of cases were limited. our study have a small population. Additionally, it is an important limitation on the part of the study that intravascular ultrasound (IVUS) was not conducted in the diagnosis of patients, as IVUS and autopsy can demonstrate atherosclerotic plaques in a wide area of the vessel lumen in patients whose coro-nary angiography is normal Conflict of Interest The authors declare no conflict of interest. References 1.Chandrasekaran B, Dar O, McDonagh T. The role of apelin in cardiovascular function and heart failure. European journal of heart failure 2008;10:725-732 2.Kleinz MJ, Davenport AP. Emerging roles of apelin in biology and medicine. Pharmacology therapeutics 2005;107:198-211 3.Ronkainen VP, Ronkainen JJ, Hanninen SL, et al. Hypoxia inducible factor regulates the cardiac expression and secretion of apelin. FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2007;21:1821-1830 4.Hashimoto T, Kihara M, Ishida J, et al. Apelin stimulates myosin light chain phosphorylation in vascular smooth muscle cells. Arteriosclerosis, thrombosis, and vascular biology 2006;26:1267-1272 5.Malyszko J, Malyszko JS, Pawlak K, Mysliwiec M. Visfatin and apelin, new adipocytokines, and their relation to endothelial function in patients with chronic renal failure. Advances in medical sciences 2008;53:32-36 6.Farkasfalvi K, Stagg MA, Coppen SR, et al. Direct effects of apelin on cardiomyocyte contractility and electrophysiology. Biochemical and biophysical research communications 2007;357:889-895 7.Hartnell GG, Parnell BM, Pridie RB. Coronary artery ectasia. Its prevalence and clinical significance in 4993 patients. British heart journal 1985;54:392-395 8.Yamanaka O, Hobbs RE. Coronary artery anomalies in 126,595 patients undergoing coronary arteriography. Catheterization and cardiovascular diagnosis 1990;21:28-40 9.Seabra-Gomes R, Somerville J, Ross DN, et al. Congenital coronary artery aneurysms. British heart journal 1974;36:329-335 10.Di Mario C, Zanchetta M, Maiolino P. Coronary aneurysms in a case of Ehlers-Danlos syndrome. Japanese heart journal 1988;29:491-496 11.Cross SJ, Lee HS, Kenmure AC, Jennings KP. Coronary artery ectasia: is it associated with myocardial ischaemia and infarction? Scottish medical journal 1993;38:28-29 12.Befeler B, Aranda MJ, Embi A, et al. Coronary artery aneurysms: study of the etiology, clinical course and effect on left ventricular function and prognosis. The American journal of medicine 1977;62:597-607 13.Lee DK, Cheng R, Nguyen T, et al. Characterization of apelin, the ligand for the APJ receptor. Journal of neurochemistry 2000;74:34-41 14.Kadoglou NP, Lampropoulos S, Kapelouzou A, et al. Serum levels of apelin and ghrelin in patients with acute coronary syndromes and established coronary artery diseaseKOZANI STUDY. Translational research : the journal of laboratory and clinical medicine 2010;155:238-246 15.Li Z, Bai Y, Hu J. Reduced apelin levels in stable angina. Internal medicine 2008;47:1951-1955 16.Rath S, Har-Zahav Y, Battler A, et al. Fate of nonobstructive aneurysmatic coronary artery disease: angiographic and clinical follow-up report. American heart journal 1985;109:785-791 17.Markis JE, Joffe CD, Cohn PF, et al. Clinical significance of coronary arterial ectasia. The American journal of cardiology 1976;37:217-222 18.Calvert JW. Cardioprotective effects of nitrite during exercise. Cardiovascular research 2011;89:499-506 19.Li L, Li L, Xie F, et al. Jagged-1/Notch3 signaling transduction pathway is involved in apelin-13-induced vascular smooth muscle cells proliferation. Acta biochimica et biophysica Sinica 2013;45:875-881 20.Azizi Y, Faghihi M, Imani A, Roghani M, Nazari A. Post-infarct treatment with [Pyr1]-apelin-13 reduces myocardial damage through reduction of oxidative injury and nitric oxide enhancement in the rat model of myocardial infarction. Peptides 2013;46:76-82 21.Tatemoto K, Takayama K, Zou MX, et al. The novel peptide apelin lowers blood pressure via a nitric oxide-dependent mechanism. Regulatory peptides 2001;99:87-92 22.Arif Yalcin A, Faruk Akturk I, Celik O, et al. Coronary Artery Ectasia Is Associated with the c.894G>T (Glu298Asp) Polymorphism of the Endothelial Nitric Oxide Synthase Gene. The Tohoku journal of experimental medicine 2014;232:137-144 23.Malyszko J, Malyszko JS, Pawlak K, Wolczynski S, Mysliwiec M. Apelin, a novel adipocytokine, in relation to endothelial function and inflammation in kidney allograft recipients. Transplantation proceedings 2008;40:3466-3469 24.Dagli N, Ozturk U, Karaca I, et al. Adiponectin levels in coronary artery ectasia. Heart and vessels 2009;24:84-89 Table 1: Baseline characteristics of the study population Grup 1 (n=26) Grup 2 (n=28) P value Age (years) 53.6 ±8.1 51.6 ± 8.8 P>0,05 0,38 Male % 19 (%73,1) 18(%64,3) P>0,05 Hypertension % 15 (%58) 12(%43) P>0,05 Diabetes Mellitus % 4 (%15) 6 (%21) p>0,05 BMI (kg/m ²) 28.1 ± 4 26.7  ±4.2 P>0,05 Smoking % 13 (%50) 12 (%46) P> 0,05 Glucose mg/dl 106 ±20 124 ±53 0.1 Creatinine mg/dl 0,86 ±0,2 0,82 ±0,1 0.38 Total cholesterol mg/dl 196 ±47 195 ±37 0.98 LDL mg/dl 128 ±42 113 ±33 0.14 HDL mg/dl 41 ±10 40 ±10 0.92 Triglyseride mg/dl 145 ±77 184 ±115 0.15
Sunday, August 4, 2019
Guilt of Commiting a Crime or Misdemeanors :: essays research papers
The Guilt of Committing a Crime or Misdemeanor      In the movie Crimes and Misdemeanors, the main character, Judah Rosenthal, make a life changing decision when he decided to kill his mistress. For Judah, there were no other alternatives to keep his affair a secret. His mistress, Delores, wanted to confront Judah’s wife Merriam to tell her about the affair that had been going on for the last past three years since Judah could not tell her himself. He knew that if Merriam found out she would not forgive him and he could not stand to see her suffer and his life crumbled to pieces. The public finding out about the affair would also had created problems for his buisness. He is known as a successful ophthalmologist who is well respected by his patients. Hiring a hit man to kill Delores is the only option to keep his affair a secret. For three years Judah and Delores carried on an affair. Their relationship had all started when they met on an airplane. She was a flight attendant and he was a rich ophthalmologist sitting in first class attending a business trip. The moment they started talking, they hit it off which soon led to an affair. She got an apartment in New York City so that she could be close to Judah. Of course, the affair was just a convenience thing for Judah, but on the other hand Delores starts to feel true feelings about him. She wanted him all to herself. One day, when Judah came home from work he found an unopened letter on the living room table sent to Merriam from Delores. Judah quickly looked around and opened the letter. The letter was about Delores confessed to Merriam about the three year love affair between her and Judah and how she wanted to meet up with Merriam. Judah was furious and put the letter into the fire. He went to Delores’s apartment and confronted her about the letter t o ask her why she would do such a thing. He also told her that thankfully that he got to the letter before Merriam did. She told him that it was time to put this affair to an end so that she and Judah could be together. Judah mentioned that he never made any promises of them being together and he would certainly tell his family about his secret. On occasions, Judah felt like he needed to talk to someone about this so he turned to one of his patients Ben who was a Jewish Rabbi that was steadily going blind.
Saturday, August 3, 2019
Effective Use of Humor in Hamlet Essay -- GCSE English Literature Cour
Effective Use of Humor in Hamlet  The use of humor in a tragic story helps to give the reader a break from the monotony of a depressing story line. â€Å"If a story were completely filled with depressing and tragic events, the readers' interest would most definitely be lost†( Bloom 91). William Shakespeare's, Hamlet is based on the tragedy of a murder of the king of Denmark, whose son must revenge his murderer. Therefore it is classified as a tragedy and if humor weren't present in the play it would be very depressing. Shakespeare ironically uses Hamlet; the main character to add the comedy bit of the play when he is the one the tragedy affects most. This humor is evident throughout the play by Hamlet. When Hamlet is upset at someone like Claudius or Polonius he will mock them in their presence without either one of them really catching on too quickly. The first one of Hamlet's stand up routines is with his uncle, Claudius in Act I, scene ii. Claudius comments on Hamlets mourning and Hamlet snaps back with a clever pun. Claudius. How is it that the clouds still hang on you? Hamlet. Not so, my lord. I am too much in the sun. (Shakespeare I.ii. ll. 66-67) When Hamlet refers to the sun he is actually saying that he feels that he is "too much of a son" to Caudius, when he is really supposed to be his nephew. The whole complication between Hamlet and Claudius is that, Hamlet's father died and then Hamlet's uncle, Claudius married his mother. This leaves Hamlet with a strange family tree because his uncle doubles as his stepfather. The line that proceeds the ones seen above also tells the reader of the awkwardness of the situation. Hamlet. A little more than kin, and less than kind! (Shakespeare I.ii. ll. 6... ...r the reader. The comedy helps break the story up a bit and gives the reader a mental breather from some of the complications in the play. While the reader is given a mental breather from the seriousness of the play they also are fed some of Hamlet's inner thought about the people he is interacting with. Hamlet is able to directly tell the other person exactly what he feels of them and by using humor, sneak it past them in most cases. Works Cited and Consulted: Bloom, Harold. Modern Critical Interpretations Of Hamlet. New York, NY: Chelsea House Publishers, 1986. Brodwin, Leonora. Hamlet Character Analysis. Monarch Notes. Brodwin's Notes Scott-Hopkins, Benjamin. "Dark Humor of Hamlet" Shakespeare-Online Shakespeare, William. "Hamlet." The Unabridged William Shakespeare. William George Clark and William Aldis Wright, ed. Running Press. 1989.
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